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Metavention Procedure Person Mobile Hero Procedure

A minimally invasive procedure that strikes a nerve.

Hepatic denervation is a one-time, minimally invasive procedure designed to permanently disrupt overactive sympathetic nerves, which may result in improved blood sugar control, reduced blood pressure and improvement in other metabolic diseases.

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Integrated Radio Frequency (iRF) Denervation System.

Animation demonstrates the iRF Denervation System used in hepatic denervation for patients with type 2 diabetes.


It’s time — time to challenge the treatment status quo.


Device Procedure 1

Unique design.

The iRF Denervation System features multiple electrodes that deliver radio frequency energy designed to permanently disrupt overactive nerves. The unique design also includes a cooling circuit that removes heat to help protect the artery wall during the procedure.

Metavention Ablation 2

Positioned precisely.

The iRF catheter is delivered through a small incision in the groin and guided into the common hepatic artery leading to the liver. Once the iRF catheter is in place, it is expanded to precisely position the electrodes against the artery wall.

Details Procedure 3

Targeted to disrupt.

The iRF Denervation System delivers radio frequency energy and coolant simultaneously in a uniform and circumferential fashion around the artery to permanently disrupt the overactive sympathetic nerves. Once the procedure is completed, the iRF catheter is removed.